Article
Evidence for a gene influencing heart rate on chromosome 5p13-14 in a meta-analysis of genome-wide scans from the NHLBI Family Blood Pressure Program.
BMC medical genetics - 1 Mar 2006
Laramie Jason M, Wilk Jemma B, Hunt Steven C, Ellison R Curtis, Chakravarti Aravinda, Boerwinkle Eric, Myers Richard H
Abstract excerpt
BACKGROUND: Elevated resting heart rate has been shown in multiple studies to be a strong predictor of cardiovascular disease. Previous family studies have shown a significant heritable component to heart rate with several groups conducting genomic linkage scans to identify quantitative trait loci. METHODS: We performed a genome-wide linkage scan to identify quantitative trait loci influencing resting heart rate...
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