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Article

SAGE programs: model-free linkage analysis for complex cardiovascular phenotypes.

Methods in molecular medicine - 1 Jan 2006

Rao Shaoqi, Wang Qing K

Abstract excerpt

A complex disease trait refers to a phenotype that does not follow simple Mendelian segregation attributable to a single gene locus, but instead may be caused by multiple disease loci, their interactions, polygenic inheritance, and environmental effects. Most cardiovascular disorders are thought to have a polygenic basis with complex interactions with environmental factors. A gene that increases or decreases the...

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PMID: 17071990
DOI: 10.1385/1-59745-159-2:61

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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