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Article

Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate gene for coronary artery disease.

American journal of human genetics - 1 Apr 2007

Wang Liyong, Hauser Elizabeth R, Shah Svati H, Pericak-Vance Margaret A, Haynes Carol, Crosslin David, Harris Marco, Nelson Sarah, Hale A Brent, Granger Christopher B, Haines Jonathan L, Jones Christopher J H, Crossman David, Seo David, Gregory Simon G, Kraus William E, Goldschmidt-Clermont Pascal J, Vance Jeffery M

Abstract excerpt

A susceptibility locus for coronary artery disease (CAD) has been mapped to chromosome 3q13-21 in a linkage study of early-onset CAD. We completed an association-mapping study across the 1-LOD-unit-down supporting interval, using two independent white case-control data sets (CATHGEN, initial and validation) to evaluate association under the peak. Single-nucleotide polymorphisms (SNPs) evenly spaced at 100-kb...

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Identifiers

PMID: 17357071
DOI: 10.1086/512981
PMCID: PMC1852708

Genes

CAD
KALRN
MYLK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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