Article
Effect of genetic variant (rs11887534) in ABCG8 gene in coronary artery disease and response to atorvastatin therapy.
Disease markers - 1 Jan 2010
Srivastava Anshika, Garg Naveen, Srivastava Anvesha, Srivastava Kshitij, Mittal Balraj
Abstract excerpt
BACKGROUND: ATP-binding cassette transporter ABCG8 plays an important role in excretion of cholesterol from liver. Common genetic polymorphisms in ABCG8 gene may genetically predispose an individual to coronary artery disease (CAD) along with response to atorvastatin therapy. Thus, we aimed to examine the role of ABCG8 D19H polymorphism (rs11887534) in susceptibility to CAD and its influence on atorvastatin...
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