Article
Common variants in the ATP-binding cassette transporter 1 gene with decreased HDL-cholesterol levels and coronary artery disease.
Archives of medical research - 1 Nov 2008
Catakoglu Alp Burak, Duman Belgin Süsleyici, Kurtoğlu Hilal, Ersöz Melike, Sener Murat, Celebi Hüseyin, Cağatay Penbe, Aytekin Vedat, Aytekin Saide
Abstract excerpt
BACKGROUND: Our aim was to determine whether the common variants within the coding sequence of ABCA1 gene affects low plasma high-density lipoprotein cholesterol (HDL-C) levels in Turkish patients with coronary artery disease (CAD). The study group was composed of 552 CAD patients, of which 251 had HDL-C levels < or =40 mg/dL, and 301 had HDL-C levels >40 mg/dL. METHODS: PCR-RFLP was used to determine the A2589G...
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