Article
ABCG5/8 variants are associated with susceptibility to coronary heart disease.
Molecular medicine reports - 1 Jun 2014
Wu Ge, Li Gui-Bin, Yao Ming, Zhang Dong-Qing, Dai Bin, Ju Chuan-Jing, Han Ming
Abstract excerpt
ATP-binding cassette sub-family G member 5 (ABCG5) and ABCG8 are members of an ATP-binding cassette transporter superfamily. ABCG5 and ABCG8 variants affected serum levels of cholesterol and were considered as risk factors for coronary heart disease (CHD). The present control study analyzed ABCG5 and ABCG8 variants in a population for association with the risk of CHD. A total of 417 CHD patients and 267 controls...
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