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Article

A novel haplotype in ABCA1 gene effects plasma HDL-C concentration.

International journal of cardiology - 31 Jan 2007

Saleheen Danish, Khanum Shaheen, Haider Shajjia R, Nazir Aisha, Ahmad Usman, Khalid Hamza, Hussain Imad, Shuja Fahad, Shahid Kamran, Habib Aisha, Frossard Philippe M

Abstract excerpt

BACKGROUND AND OBJECTIVES: ATP-binding cassette transporter 1 (ABCA1) is a trans-membrane protein responsible for the efflux of cholesterol and phospholipids across the cell membrane, an essential step in the reverse cholesterol transport system. This study investigates the effect of five non-synonymous SNPs of ABCA1 gene on plasma HDL-C levels in Pakistani individuals free of ischemic heart disease and stroke....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16806540
DOI: 10.1016/j.ijcard.2005.12.020

Genes

ABCA1

Provenance

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