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Article

ABCG8 gene polymorphisms, plasma cholesterol concentrations, and risk of cardiovascular disease in familial hypercholesterolemia.

Atherosclerosis - 1 Jun 2009

Koeijvoets Kristel C M C, van der Net Jeroen B, Dallinga-Thie Geesje M, Steyerberg Ewout W, Mensink Ronald P, Kastelein John J P, Sijbrands Eric J G, Plat Jogchum

Abstract excerpt

Elevated plasma plant sterol concentrations may be a risk factor of cardiovascular disease (CVD). Polymorphisms in the ABCG8 gene have been identified that contribute to the variation in plasma concentrations of plant sterols. However, data on the direct relationship of ABCG8 gene polymorphisms with CVD are lacking. Therefore, we examined associations between the D19H and T400K polymorphisms in the ABCG8 gene and...

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Source

Identifiers

PMID: 18977479
DOI: 10.1016/j.atherosclerosis.2008.09.018

Genes

ABCG8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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