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Article

ABCG5/G8 polymorphisms and markers of cholesterol metabolism: systematic review and meta-analysis.

Journal of lipid research - 1 Oct 2010

Jakulj Lily, Vissers Maud N, Tanck Michael W T, Hutten Barbara A, Stellaard Frans, Kastelein John J P, Dallinga-Thie Geesje M

Abstract excerpt

Genetic variation at the ABCG5/G8 locus has been associated with markers of cholesterol homeostasis. As data originate from small-scale studies, we performed a meta-analysis to study these associations in a large dataset. We first investigated associations between five common ABCG5/G8 polymorphisms (p.Q604E, p.D19H, p.Y54C, p.T400K, and p.A632V) and plasma sterol levels in 245 hypercholesterolaemic individuals....

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Identifiers

PMID: 20581104
DOI: 10.1194/jlr.M008128
PMCID: PMC2936756

Genes

ABCG5
ABCG8

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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