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Article

The genetics of the thyroid stimulating hormone receptor: history and relevance.

Thyroid : official journal of the American Thyroid Association - 1 Jul 2010

Davies Terry F, Yin Xiaoming, Latif Rauf

Abstract excerpt

BACKGROUND: The thyroid stimulating hormone receptor (TSHR) is the key regulator of thyrocyte function. The gene for the TSHR on chromosome 14q31 has been implicated as coding for the major autoantigen in the autoimmune hyperthyroidism of Graves' disease (GD) to which T cells and autoantibodies are directed. SUMMARY: The TSHR is a seven-transmembrane domain receptor that undergoes complex posttranslational...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20578897
DOI: 10.1089/thy.2010.1638
PMCID: PMC2935345

Genes

TSHR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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