Article
Refined association of TSH receptor susceptibility locus to Graves' disease in the Chinese Han population.
European journal of endocrinology - 1 Jan 2014
Liu Bing-Li, Yang Shao-Ying, Liu Wei, Xue Li-Qiong, Chen Xia, Pan Chun-Ming, Gu Zhao-Hui, Zhan Ming, Zhang Xiao-Mei, Liang Jun, Gao Guan-Qi, Du Wen-Hua, Yuan Guo-Yue, Ying Ru, Zhao Shuang-Xia, Song Huai-Dong
Abstract excerpt
BACKGROUND: Convincing evidence has demonstrated the association of TSH receptor (TSHR) with Graves' disease (GD) in the Chinese Han population. OBJECTIVE: The aim of this study was to identify the causal variants for GD in the region encompassing TSHR by a refining association study. DESIGN AND METHODS: GD patients (1536) and 1516 sex-matched controls were recruited in the first stage, and an additional 3832 GD...
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