Article
Association between thyroid stimulating hormone receptor gene intron polymorphisms and autoimmune thyroid disease in a Chinese Han population.
Endocrine journal - 1 Jan 2012
Liu Lin, Wu Hu-qun, Wang Qiong, Zhu Yuan-feng, Zhang Wen, Guan Li-juan, Zhang Jin-an
Abstract excerpt
Autoimmune thyroid disease (AITD) is a multifactorial disease with a genetic susceptibility and environmental factors. The thyroid stimulating hormone receptor gene (TSHR) which is expressed on the surface of the thyroid epithelial cell is thought to be the main auto-antigen and a significant candidate for genetic susceptibility to AITD. This case-control study aimed at evaluating the association between single...
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