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Article

DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast.

Nucleic acids research - 11 Jun 1991

Mellor J, Rathjen J, Jiang W, Barnes C A, Dowell S J

Abstract excerpt

The centromere and promoter factor 1 (CPF1) binds specifically in vitro and in vivo to an octanucleotide (RTCACRTG). This sequence is found in the centromere DNA element I (CDEI) of yeast centromeres and upstream from a number of transcription units including MET25, GAL2 and TRP1. Inactivation of the CPF1 gene results in three phenotypes; slow growth, a partial loss of centromere function and methionine...

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PMID: 2057354
DOI: 10.1093/nar/19.11.2961
PMCID: PMC328258

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DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast.PMID 2057354Read ↗

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