Article
Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription.
Molecular and cellular biology - 1 Apr 1995
O'Connell K F, Surdin-Kerjan Y, Baker R E
Abstract excerpt
Saccharomyces cerevisiae general regulatory factor CP1 (encoded by the gene CEP1) is required for optimal chromosome segregation and methionine prototrophy. MET16-CYC1-lacZ reporter constructs were used to show that MET16 5'-flanking DNA contains a CP1-dependent upstream activation sequence (UAS). Activity of the UAS required an intact CP1-binding site, and the effects of cis-acting mutations on CP1 binding and...
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