Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy.

Cell - 4 May 1990

Cai M, Davis R W

Abstract excerpt

The centromere and its binding proteins constitute the kinetochore structure of metaphase chromosomes, which is crucial for the high accuracy of the chromosome segregation process. Isolation and analysis of the gene encoding a centromere binding protein from the yeast S. cerevisiae, CBF1, are described in this paper. DNA sequence analysis of the CBF1 gene reveals homology with the transforming protein myc and a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA-Binding Proteins

Share to Fungal Proteins

Share to Genes, Fungal

Share to Genotype

Share to Molecular Sequence Data

Source

Identifiers

PMID: 2185892
DOI: 10.1016/0092-8674(90)90525-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy.PMID 2185892Read ↗

The centromere-binding factor Cbf1p from Candida albicans complements the methionine auxotrophic phenotype of Saccharomyces cerevisiae.Semantic proximity Read ↗

Point mutations that separate the role of Saccharomyces cerevisiae centromere binding factor 1 in chromosome segregation from its role in transcriptional activation.Semantic proximity Read ↗

Functional characterization of CaCBF1, the Candida albicans homolog of centromere binding factor 1.Semantic proximity Read ↗

Multifunctional centromere binding factor 1 is essential for chromosome segregation in the human pathogenic yeast Candida glabrata.Semantic proximity Read ↗

Identification of Novel α-N-Methylation of CENP-B That Regulates Its Binding to the Centromeric DNASemantic proximity Read ↗

Functional redundancies, distinct localizations and interactions among three fission yeast homologs of centromere protein-B.Semantic proximity Read ↗

The elusive centromere: sequence divergence and functional conservation.Semantic proximity Read ↗

Fission Yeast CENP-C (Cnp3) Plays a Role in Restricting the Site of CENP-A Accumulation.Semantic proximity Read ↗

DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast.Semantic proximity Read ↗

Genome-wide analysis reveals a cell cycle-dependent mechanism controlling centromere propagation.Semantic proximity Read ↗

Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae.Semantic proximity Read ↗

Chromatin assembly factor I and Hir proteins contribute to building functional kinetochores in S. cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.