Article
Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy.
Cell - 4 May 1990
Cai M, Davis R W
Abstract excerpt
The centromere and its binding proteins constitute the kinetochore structure of metaphase chromosomes, which is crucial for the high accuracy of the chromosome segregation process. Isolation and analysis of the gene encoding a centromere binding protein from the yeast S. cerevisiae, CBF1, are des...
Topics
- Amino Acid Sequence
- Base Sequence
- Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
- Centromere
- Chromosomes
- Chromosomes, Fungal
- Cloning, Molecular
- DNA-Binding Proteins
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genotype
- Methionine
- Molecular Sequence Data
- Oligonucleotide Probes
- Protein-Tyrosine Kinases
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-myc