Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutational analysis of the Saccharomyces cerevisiae general regulatory factor CP1.

Nucleic acids research - 25 Aug 1993

Masison D C, O'Connell K F, Baker R E

Abstract excerpt

The Saccharomyces cerevisiae general regulatory factor CP1, a helix-loop-helix protein that binds the centromere DNA element I (CDEI) of yeast centromeres, is required in yeast for optimal centromere function and for methionine prototrophy. Mutant alleles of CEP1, the gene encoding CP1, were generated by linker insertion, 5'- and 3'-deletion, and random mutagenesis and assayed for DNA binding activity and their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to DNA-Binding Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Fungal Proteins

Share to Molecular Sequence Data

Share to Phenotype

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 8371988
DOI: 10.1093/nar/21.17.4133
PMCID: PMC310021

Genes

MET
TFEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutational analysis of the Saccharomyces cerevisiae general regulatory factor CP1.PMID 8371988Read ↗

Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CP1.Semantic proximity Read ↗

DNA binding of CPF1 is required for optimal centromere function but not for maintaining methionine prototrophy in yeast.Semantic proximity Read ↗

Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription.Semantic proximity Read ↗

Mutations synthetically lethal with cep1 target S. cerevisiae kinetochore components.Semantic proximity Read ↗

Point mutations that separate the role of Saccharomyces cerevisiae centromere binding factor 1 in chromosome segregation from its role in transcriptional activation.Semantic proximity Read ↗

A suppressor of a centromere DNA mutation encodes a putative protein kinase (MCK1).Semantic proximity Read ↗

Possible cross-regulation of phosphate and sulfate metabolism in Saccharomyces cerevisiae.Semantic proximity Read ↗

Multifunctional centromere binding factor 1 is essential for chromosome segregation in the human pathogenic yeast Candida glabrata.Semantic proximity Read ↗

Yeast centromere binding protein CBF1, of the helix-loop-helix protein family, is required for chromosome stability and methionine prototrophy.Semantic proximity Read ↗

Interactions of the yeast centromere and promoter factor, Cpf1p, with the cytochrome c1 upstream region and functional implications on regulated gene expression.Semantic proximity Read ↗

The centromere-binding factor Cbf1p from Candida albicans complements the methionine auxotrophic phenotype of Saccharomyces cerevisiae.Semantic proximity Read ↗

Determination of the binding constants of the centromere protein Cbf1 to all 16 centromere DNAs of Saccharomyces cerevisiae.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.