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Article

PIK3CA mutations in KRAS and BRAF wild type colorectal cancer patients. A study of Spanish population.

Molecular biology reports - 1 Feb 2011

Herreros-Villanueva Marta, Gomez-Manero Noemí, Muñiz Pilar, García-Girón Carlos, Coma del Corral Maria Jesús

Abstract excerpt

The objective of the work was to study PIK3CA mutations in wild type KRAS and BRAF colorectal cancer. Clinicopathological data and paraffin-embedded specimens were collected on 73 patients who underwent colorectal resections at General Yagüe Hospital in Burgos. KRAS, BRAF and PIK3CA status were analyzed by real-time PCR in all patients. PIK3CA mutations were present in 8.22% of wild type KRAS and BRAF colorectal...

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Identifiers

PMID: 20571907
DOI: 10.1007/s11033-010-0236-6

Genes

BRAF
KRAS
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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