PIK3CA mutations in small bowel adenocarcinoma.

Abstract excerpt

AIMS AND BACKGROUND: PIK3CA mutations involving exons 9 and 20 are among the most common aberrations seen in human malignancies. The identification of PIK3CA mutations in small bowel adenocarcinoma (SBA) is sparse. There is some evidence that tumors with this mutation may be a good target for inhibitors of the PI3K pathway. CASE REPORT: We report an exon 9 (G1624A: E542K) hot spot mutation in a 69-year-old man...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adenocarcinoma
• Share to Aged
• Share to Class I Phosphatidylinositol 3-Kinases
• Share to Disease-Free Survival
• Share to Exons
• Share to Mutation
• Share to Phosphatidylinositol 3-Kinases