Article
The Landscape of PIK3CA Mutations in Colorectal Cancer.
Clinical colorectal cancer - 1 Sept 2021
Voutsadakis Ioannis A
Abstract excerpt
BACKGROUND: Colorectal cancer is one of the most common malignancies in both men and women. Despite progress in the treatment of the disease, metastatic colorectal cancer remains lethal with a median survival slightly surpassing 2 years and commonly for some cases a more aggressive course. New therapies are urgently needed based on a better understanding of the molecular pathogenesis of the disease. METHODS: The...
Topics
- Class I Phosphatidylinositol 3-Kinases
- Colorectal Neoplasms
- Female
- Humans
- Male
- Mutation
- Phosphatidylinositol 3-Kinases
- Prognosis
