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Article

[BRAF gene mutation in wild-type KRAS patients with colorectal cancers].

Revista medica de Chile - 1 Jan 2014

Roa Iván, Game Anakaren, Bizama Carolina, Schalper Kurt

Abstract excerpt

BACKGROUND: In colorectal cancer, BRAF and KRAS mutation are mutually exclusive, but both are independent prognostic factors for the disease. AIM: To determine the frequency of BRAF V600E mutation in colorectal cancer. MATERIAL AND METHODS: A KRAS mutation study was carried out in 100 tissue samples of primary and metastatic adenocarcinomas of colon and rectum from patients aged 61.1 ± 62 years (56 women)....

Topics

Adenocarcinoma
Colorectal Neoplasms
Female
Genotype
Humans
Male
Middle Aged
Mutation
Neoplasm Staging
Polymorphism, Restriction Fragment Length
Proto-Oncogene Proteins
Proto-Oncogene Proteins B-raf

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins p21(ras)

ras Proteins

Source

Identifiers

PMID: 24861115
DOI: 10.4067/S0034-98872014000100009

Genes

KRAS
BRAF
EGFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-24861115-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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