Article
BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.
Nucleic acids research - 1 Nov 2010
Cohen Stephanie M, Chastain Paul D, Rosson Gary B, Groh Beezly S, Weissman Bernard E, Kaufman David G, Bultman Scott J
Abstract excerpt
For DNA replication to occur, chromatin must be remodeled. Yet, we know very little about which proteins alter nucleosome occupancy at origins and replication forks and for what aspects of replication they are required. Here, we demonstrate that the BRG1 catalytic subunit of mammalian SWI/SNF-related complexes co-localizes with origin recognition complexes, GINS complexes, and proliferating cell nuclear antigen...
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