Article
Investigation of multiple susceptibility loci for inflammatory bowel disease in an Italian cohort of patients.
PloS one - 1 Jan 2011
Latiano Anna, Palmieri Orazio, Latiano Tiziana, Corritore Giuseppe, Bossa Fabrizio, Martino Giuseppina, Biscaglia Giuseppe, Scimeca Daniela, Valvano Maria Rosa, Pastore Maria, Marseglia Antonio, D'Incà Renata, Andriulli Angelo, Annese Vito
Abstract excerpt
BACKGROUND: Recent GWAs and meta-analyses have outlined about 100 susceptibility genes/loci for inflammatory bowel diseases (IBD). In this study we aimed to investigate the influence of SNPs tagging the genes/loci PTGER4, TNFSF15, NKX2-3, ZNF365, IFNG, PTPN2, PSMG1, and HLA in a large pediatric- and adult-onset IBD Italian cohort. METHODS: Eight SNPs were assessed in 1,070 Crohn's disease (CD), 1,213 ulcerative...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.