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Article

Geno- and phenotyping and immunogenicity of HNA-3.

Transfusion - 1 Jan 2011

Reil Angelika, Wesche Jan, Greinacher Andreas, Bux Juergen

Abstract excerpt

BACKGROUND: Alloantibodies directed against the human neutrophil alloantigen (HNA)-3a are frequently implicated in severe and fatal transfusion-related acute lung injury (TRALI). The HNA-3a/3b system results from a single-nucleotide exchange (461G>A; Arg154Gln) in the choline transporter-like protein 2 gene. Genotyping may allow identification of blood donors at risk to develop HNA-3a antibodies. STUDY DESIGN AND...

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Identifiers

PMID: 20561293
DOI: 10.1111/j.1537-2995.2010.02751.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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