Article
Characterization of the human neutrophil alloantigen-3a.
Nature medicine - 1 Jan 2010
Greinacher Andreas, Wesche Jan, Hammer Elke, Fürll Birgitt, Völker Uwe, Reil Angelika, Bux Jürgen
Abstract excerpt
Transfusion-related acute lung injury (TRALI) is a frequent cause of transfusion-associated morbidity and mortality. Severe TRALI is often due to antibodies in blood components directed against the human neutrophil alloantigen-3a (HNA-3a). We show here that the HNA-3a antigen arises from a nucleo...
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