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Article

The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution.

Blood - 11 Mar 2010

Curtis Brian R, Cox Nancy J, Sullivan Mia J, Konkashbaev Anuar, Bowens Krista, Hansen Kirk, Aster Richard H

Abstract excerpt

The molecular basis of the HNA-3a/b (5b/a) leukocyte antigen system has not yet been defined despite evidence that HNA-3a-specific antibodies are particularly prone to cause severe, often fatal, transfusion-related lung injury. We used genome-wide single nucleotide polymorphism scanning and seque...

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Identifiers

PMID: 20040764
DOI: 10.1182/blood-2009-11-248336
PMCID: PMC2837332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20040764-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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