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Article

Implication of transfected cell lines for the detection of alloantibodies against human neutrophil antigen-3.

Transfusion - 1 Mar 2012

Bayat Behnaz, Tjahjono Yudy, Werth Silke, Berghöfer Heike, Reil Angelika, Kroll Hartmut, Sachs Ulrich J, Santoso Sentot

Abstract excerpt

BACKGROUND: Alloantibodies against human neutrophil antigen-3 (HNA-3) are responsible for the fatalities reported in transfusion-related acute lung injury. Consequently, reliable detection of these alloantibodies is mandatory to improve blood transfusion safety. In this study, we developed stable cell lines for the detection of HNA-3 antibodies. STUDY DESIGN AND METHODS: HEK293T were transfected with HNA-3a or...

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Identifiers

PMID: 21883263
DOI: 10.1111/j.1537-2995.2011.03303.x

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