Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation of the HNA-3a encoding gene.

Transfusion - 1 Nov 2011

Flesch Brigitte K, Reil Angelika, Bux Jürgen

Abstract excerpt

BACKGROUND: Antibodies against the human neutrophil alloantigen-3a (HNA-3a) play an important role in transfusion-related acute lung injury. The HNA-3a and -3b alloantigens result from a single-nucleotide exchange in the choline transporter-like protein 2 gene (CTL2). We sought for additional polymorphisms that might impair antibody binding to or genotyping of the HNA-3a or -3b antigens. STUDY DESIGN AND METHODS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Isoantigens
Share to DNA, Complementary
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Sera

Share to Polymerase Chain Reaction

Share to Polymorphism, Single Nucleotide

Share to Sequence Analysis, DNA

Source

Identifiers

PMID: 21564101
DOI: 10.1111/j.1537-2995.2011.03155.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation of the HNA-3a encoding gene.PMID 21564101Read ↗

Geno- and phenotyping and immunogenicity of HNA-3.Semantic proximity Read ↗

The neutrophil alloantigen HNA-3a (5b) is located on choline transporter-like protein 2 and appears to be encoded by an R>Q154 amino acid substitution.Semantic proximity Read ↗

Implication of transfected cell lines for the detection of alloantibodies against human neutrophil antigen-3.Semantic proximity Read ↗

Characterization of the human neutrophil alloantigen-3a.Semantic proximity Read ↗

Full-length nucleotide sequences of 30 common SLC44A2 alleles encoding human neutrophil antigen-3.Semantic proximity Read ↗

Human neutrophil antigen 3 genotype impacts neutrophil-mediated endothelial cell cytotoxicity in a two-event model of TRALI.Semantic proximity Read ↗

Molecular Genetics of the Human Neutrophil AntigensSemantic proximity Read ↗

Frequencies of SLC44A2 alleles encoding human neutrophil antigen‐3 variants in the African American populationSemantic proximity Read ↗

Determination of neutrophil antigen HNA-3a and HNA-3b genotype frequencies in six racial groups by high-throughput 5' exonuclease assay.Semantic proximity Read ↗

Anti-HNA testing of allo-exposed COVID-19 convalescent plasma donors including genetic human neutrophil antigen screening to prevent anti-HNA antibody-mediated transfusion-related acute lung injury.Semantic proximity Read ↗

Spotlight on pathogenesis of TRALI: HNA-3a (CTL2) antibodies.Semantic proximity Read ↗

Phenotyping and Genotyping of HNA: Prevalence, Risk of Alloimmunization, and HNA Incompatibilities in IndiansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.