Article
Risk estimation of HNA-3 incompatibility and alloimmunization in Thai populations.
PloS one - 1 Jan 2015
Nathalang Oytip, Intharanut Kamphon, Siriphanthong Kanokpol, Nathalang Siriporn, Leetrakool Nipapan
Abstract excerpt
Severe transfusion-related acute lung injury (TRALI) is often due to antibodies in blood components directed against human neutrophil antigen (HNA)-3a. This study aimed to report the genotype frequencies of the HNA-3 system and to estimate the potential risk of HNA-3 incompatibility and alloimmunization in two Thai populations. Eight hundred DNA samples obtained from 500 unrelated healthy blood donors at the...
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