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Article

Molecular Genetics of the Human Neutrophil Antigens

1 Jan 2018

Abstract excerpt

Background and Objective: Antibodies to human neutrophil antigens (HNAs) have been implicated in transfusion-related acute lung injury and allo- and autoimmune neutropenia. To date, five HNA systems are assigned, and during the last decades enormous efforts have been undertaken to identify the underlying genes and to characterize the antigens. This review of the literature will provide the current genetic,...

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PMID: 30498408
DOI: 10.1159/000491031

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