Article
Phylogeny and resistance profiles of HIV-1 POL sequences from rectal biopsies and blood.
Journal of medical virology - 1 Jul 2010
Katzenstein T L, Petersen A B, Storgaard M, Obel N, Jensen-Fangel S, Nielsen C, Jørgensen L B
Abstract excerpt
The phylogeny and resistance profiles of human immunodeficiency virus type 1 (HIV-1) protease (PR) and reverse transcriptase (RT) sequences were compared among six patients with HIV-1 who had received numerous treatments. RNA and DNA fractions were obtained from concurrent blood and rectal biopsy...
Topics
- Amino Acid Sequence
- Anti-HIV Agents
- Antiretroviral Therapy, Highly Active
- Colon
- Drug Resistance, Multiple, Viral
- Genes, pol
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Intestinal Mucosa
- Leukocytes, Mononuclear
- Molecular Sequence Data
- Mutation
- Phylogeny
- Rectum
- Sequence Alignment