Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phylogeny and resistance profiles of HIV-1 POL sequences from rectal biopsies and blood.

Journal of medical virology - 1 Jul 2010

Katzenstein T L, Petersen A B, Storgaard M, Obel N, Jensen-Fangel S, Nielsen C, Jørgensen L B

Abstract excerpt

The phylogeny and resistance profiles of human immunodeficiency virus type 1 (HIV-1) protease (PR) and reverse transcriptase (RT) sequences were compared among six patients with HIV-1 who had received numerous treatments. RNA and DNA fractions were obtained from concurrent blood and rectal biopsy samples. Phylogenetic trees and resistance profiles showed that the rectal mucosa and the peripheral blood mononuclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to HIV-1
Share to HIV Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Leukocytes, Mononuclear

Share to Molecular Sequence Data

Share to Mutation

Share to Phylogeny

Share to Sequence Alignment

Source

Identifiers

PMID: 20513071
DOI: 10.1002/jmv.21796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phylogeny and resistance profiles of HIV-1 POL sequences from rectal biopsies and blood.PMID 20513071Read ↗

Mutational patterns of paired blood and rectal biopsies in HIV-infected patients on HAART.Semantic proximity Read ↗

Evidence of genotypic resistance diversity of archived and circulating viral strains in blood and semen of pre-treated HIV-infected men.Semantic proximity Read ↗

Despite high concordance, distinct mutational and phenotypic drug resistance profiles in human immunodeficiency virus type 1 RNA are observed in gastrointestinal mucosal biopsy specimens and peripheral blood mononuclear cells compared with plasma.Semantic proximity Read ↗

Greater diversity of HIV DNA variants in the rectum compared to variants in the blood in patients without HAART.Semantic proximity Read ↗

Profiling resistance-related mutations in the protease region of the pol gene: single genome sequencing of HIV in plasma and peripheral blood mononuclear cells.Semantic proximity Read ↗

Differential virus evolution in blood and genital tract of HIV-infected females: evidence for the involvement of drug and non-drug resistance-associated mutations.Semantic proximity Read ↗

HIV-1 drug resistance in variants from the female genital tract and plasma.Semantic proximity Read ↗

Emergence of protease inhibitor resistance-associated mutations in plasma HIV-1 precedes that in proviruses of peripheral blood mononuclear cells by more than a year.Semantic proximity Read ↗

Phylogenetic investigation of transmission pathways of drug-resistant HIV-1 utilizing pol sequences derived from resistance genotyping.Semantic proximity Read ↗

Distinct mutational drug resistance profiles of HIV-1 RNA in plasma and culture isolates of patients receiving antiretroviral therapy.Semantic proximity Read ↗

Differential evolution of cell-associated virus in blood and genital tract of HIV-infected females undergoing HAART.Semantic proximity Read ↗

Reverse transcriptase and protease sequence evolution in two HIV-1-infected couples.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.