Article
Evidence of genotypic resistance diversity of archived and circulating viral strains in blood and semen of pre-treated HIV-infected men.
AIDS (London, England) - 20 Feb 2004
Ghosn Jade, Viard Jean-Paul, Katlama Christine, de Almeida Marta, Tubiana Roland, Letourneur Franck, Aaron Laurent, Goujard Cécile, Salmon Dominique, Leruez-Ville Marianne, Rouzioux Christine, Chaix Marie-Laure
Abstract excerpt
OBJECTIVE: To study the genetic diversity of drug-resistant HIV strains present in blood and in semen, especially those archived in peripheral blood mononuclear cells (PBMC) and non-sperm cells (NSC). METHODS: Paired blood and semen samples were collected from twenty heavily pre-treated HIV-infected men. HIV RNA in blood plasma (BP) and seminal plasma (SP), as well as proviral DNA in PBMC and NSC were quantified...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.