Article
Phylogenetic investigation of transmission pathways of drug-resistant HIV-1 utilizing pol sequences derived from resistance genotyping.
Journal of acquired immune deficiency syndromes (1999) - 1 Sept 2008
Kaye Matthew, Chibo Doris, Birch Chris
Abstract excerpt
OBJECTIVES: To investigate the nature of transmission links existing between patients recently infected with HIV strains containing transmitted drug resistance (TDR) mutations. METHODS: Virus from 63 individuals recently infected with HIV-1 containing TDR mutations was analyzed phylogenetically to determine virological links. Phylogenetic trees were reconstructed using maximum likelihood and distance-based...
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