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Article

Emergence of protease inhibitor resistance-associated mutations in plasma HIV-1 precedes that in proviruses of peripheral blood mononuclear cells by more than a year.

Journal of acquired immune deficiency syndromes (1999) - 1 Sept 2003

Bi Xiuqiong, Gatanaga Hiroyuki, Ida Setsuko, Tsuchiya Kiyoto, Matsuoka-Aizawa Saori, Kimura Satoshi, Oka Shinichi

Abstract excerpt

HIV-1 genotype assay using plasma viruses has been widely applied for detection of resistant viruses in infected individuals, whereas there are only a few reports about proviral genotype in peripheral blood mononuclear cells (PBMCs). To determine which sample, plasma or PBMC, should be used for early detection of drug-resistant viruses during antiretroviral treatment, we analyzed 275 plasma-derived and 211...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 14501787
DOI: 10.1097/00126334-200309010-00001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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