Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Reverse transcriptase and protease sequence evolution in two HIV-1-infected couples.

Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2002

Palmer Sarah, Vuitton Dominique, Gonzales Matthew J, Bassignot Agnés, Shafer Robert W

Abstract excerpt

We analyzed the reverse transcriptase (RT) and protease sequences of HIV-1 isolates obtained over 7 years from two couples with known transmission histories. Phylogenetic trees constructed from the sequence data reflected the known transmission histories, despite the fact that the drug resistance mutations were most consistent with the drug treatment histories. However, the RT sequences from one couple diverged...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-HIV Agents
Share to Drug Resistance, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Viral

Share to HIV Infections

Share to HIV Protease

Share to HIV Reverse Transcriptase

Share to Sexual Partners

Source

Open in PubMed Open full text

Identifiers

PMID: 12439203
DOI: 10.1097/00126334-200211010-00003
PMCID: PMC2628486

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Reverse transcriptase and protease sequence evolution in two HIV-1-infected couples.PMID 12439203Read ↗

Human immunodeficiency virus reverse transcriptase and protease sequence database.Semantic proximity Read ↗

Human Immunodeficiency Virus Reverse Transcriptase and Protease Sequence Database.Semantic proximity Read ↗

Identification of a transmission chain of HIV type 1 containing drug resistance-associated mutations.Semantic proximity Read ↗

pol gene diversity of five human immunodeficiency virus type 1 subtypes: evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and D.Semantic proximity Read ↗

HIV-1 Protease and reverse-transcriptase mutations: correlations with antiretroviral therapy in subtype B isolates and implications for drug-resistance surveillance.Semantic proximity Read ↗

Lack of detectable human immunodeficiency virus type 1 superinfection during 1072 person-years of observation.Semantic proximity Read ↗

Phylogenetic analysis of human immunodeficiency virus type 1 subtype C env gp120 sequences among four drug-naive families following subsequent heterosexual and vertical transmissions.Semantic proximity Read ↗

Parallel evolution of drug resistance in HIV: failure of nonsynonymous/synonymous substitution rate ratio to detect selection.Semantic proximity Read ↗

Evolution of human immunodeficiency virus type 1 nucleotide sequence diversity among close contacts.Semantic proximity Read ↗

Short communication: Nucleotide variation and positively selected sites in HIV type 1 reverse transcriptase among heterosexual transmission pairs.Semantic proximity Read ↗

HIV-1 subtype B protease and reverse transcriptase amino acid covariation.Semantic proximity Read ↗

Sequential transmission and long-term persistence of an HIV strain partially resistant to protease inhibitors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.