Article
Differential virus evolution in blood and genital tract of HIV-infected females: evidence for the involvement of drug and non-drug resistance-associated mutations.
Virology - 1 Jul 2004
Tirado Grissell, Jove Gloria, Kumar Rakesh, Noel Richard J, Reyes Evelyn, Sepulveda Gladys, Yamamura Y, Kumar Anil
Abstract excerpt
There is increasing evidence that male or female genital tract represent a distinct replication compartment for human immunodeficiency virus type 1 (HIV-1) and that such compartments may serve as a virus reservoir. Forty-four paired plasma and vaginal samples from HIV-infected females undergoing HAART were collected to examine the viral responses to antiretroviral therapy and to assess the possible role of the...
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