Article
Greater diversity of HIV DNA variants in the rectum compared to variants in the blood in patients without HAART.
Journal of medical virology - 1 Sept 2011
Avettand-Fenoel Véronique, Hocqueloux Laurent, Müller-Trutwin Michaela, Prazuck Thierry, Melard Adeline, Chaix Marie-Laure, Agoute Eric, Michau Christophe, Rouzioux Christine
Abstract excerpt
The gut-associated lymphoid tissue represents the largest reservoir of HIV-1. Improving knowledge of this reservoir by studying the diversity of viral population is a key step towards understanding the pathogenesis and dynamics of HIV. Obtaining samples is difficult and little information is available on gut viral quasispecies during the course of infection in humans. The aim of this study was to characterize...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
