Article
Distinct mutational drug resistance profiles of HIV-1 RNA in plasma and culture isolates of patients receiving antiretroviral therapy.
Intervirology - 1 Jan 2002
Debiaggi Marizia, Bruno Raffaele, Sacchi Paolo, Achilli Giorgio, Romero Egidio, Filice Gaetano
Abstract excerpt
The differences in profiles of HIV mutational drug resistance between paired plasma samples and culture isolates were analyzed in treated and untreated HIV-infected patients. The DNA sequence of the entire protease gene and codons 1-320 of the reverse transcriptase gene was analyzed from the pair...
Topics
- Antiretroviral Therapy, Highly Active
- Drug Resistance, Viral
- Genotype
- HIV Infections
- HIV Protease
- HIV Reverse Transcriptase
- HIV-1
- Humans
- Leukocytes, Mononuclear
- Mutation
- Phenotype
- RNA, Viral