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Article

Affective and cognitive effects of global deletion of alpha3-containing gamma-aminobutyric acid-A receptors.

Behavioural pharmacology - 1 Sept 2008

Fiorelli Roberto, Rudolph Uwe, Straub Carolin J, Feldon Joram, Yee Benjamin K

Abstract excerpt

Gamma-aminobutyric acid (GABA)A receptors characterized by the presence of the alpha3 subunit are the major GABAA receptor subtype expressed in brain stem monoaminergic nuclei. These alpha3-GABAA receptors are therefore in a unique position to regulate monoaminergic functions. To characterize the functional properties of alpha3-GABAA receptors, we present a preliminary assessment of the expression of affective...

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PMID: 18690113
DOI: 10.1097/FBP.0b013e32830dc0c7

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