Article
Evidence of association between gamma-aminobutyric acid type A receptor genes located on 5q34 and female patients with mood disorders.
Neuroscience letters - 25 Sept 2003
Yamada Kazuo, Watanabe Akiko, Iwayama-Shigeno Yoshimi, Yoshikawa Takeo
Abstract excerpt
Pharmacological evidence suggests the involvement of gamma-aminobutyric acid (GABA) perturbation in the etiology of mood disorders. A linkage study has detected chromosomal area 5q34, where GABA type A (GABA(A)) receptor subunit genes are mapped, as a susceptibility region for mood disorders, making these genes compelling candidates for such diseases. Our prior quantitative trait loci (QTL) analysis of mouse...
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