Article
Identification of quantitative trait Loci that affect aggressive behavior in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Feb 2002
Brodkin Edward S, Goforth Sarah A, Keene Angela H, Fossella John A, Silver Lee M
Abstract excerpt
Despite the previous development of single-gene knock-out mice that exhibit alterations in aggressive behavior, very little progress has been made toward identifying the natural gene variants (alleles) that contribute to individual or strain differences in aggression. Whereas most inbred mouse strains show an intermediate level of inter-male aggression in the resident-intruder or dangler behavioral tests,...
Topics
- Aggression
- Animals
- Behavior, Animal
- Chromosome Mapping
- Diacylglycerol Kinase
- Genetic Variation
- Genotype
- Inbreeding
- Mice
- Mice, Inbred Strains
- Phenotype