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Article

Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes.

Hepatology (Baltimore, Md.) - 1 Jun 1991

Enomoto N, Takase S, Takada N, Takada A

Abstract excerpt

To clarify the pathogenetic role of acetaldehyde in the development of alcoholic liver disease, genotyping of aldehyde dehydrogenase-2 genes was performed and the clinical features of the alcoholic liver disease patients with different genotypes were compared. Genotyping of aldehyde dehydrogenase-2 was performed in 47 patients with alcoholic liver disease using the polymerase chain reaction and slot-blot...

Topics

Alcohol Drinking
Aldehyde Dehydrogenase
Genes
Genotype
Heterozygote
Homozygote
Humans
Liver Diseases, Alcoholic
Mutation
Reference Values

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2050324

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2050324-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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