Article
Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes.
Hepatology (Baltimore, Md.) - 1 Jun 1991
Enomoto N, Takase S, Takada N, Takada A
Abstract excerpt
To clarify the pathogenetic role of acetaldehyde in the development of alcoholic liver disease, genotyping of aldehyde dehydrogenase-2 genes was performed and the clinical features of the alcoholic liver disease patients with different genotypes were compared. Genotyping of aldehyde dehydrogenase-2 was performed in 47 patients with alcoholic liver disease using the polymerase chain reaction and slot-blot...
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