Article
Assessment of a difference in ALDH2 heterozygotes and alcoholic liver injury.
Alcoholism, clinical and experimental research - 1 Aug 2002
Nagata Naruhiko, Hiyoshi Mineyoshi, Shiozawa Hirokazu, Shiraishi Koichi, Watanabe Norihito, Tsuda Michio, Matsuzaki Shohei
Abstract excerpt
We have speculated that the degree of liver dysfunction in alcoholic liver disease with ALDH2*1/2*2 may be less pronounced than that with ALDH2*1/2*1. In the present study, outpatients with alcoholic liver injury were examined for ALDH2 genotype and biochemical data. The number of patients was 29 cases of nonspecific changes, 16 cases of fatty liver, 5 cases of liver fibrosis, and 44 cases of liver cirrhosis....
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