Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism.

doi:10.1176/ajp.152.8.1219

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Article

Alcohol and aldehyde dehydrogenase polymorphisms and the risk for alcoholism.

The American journal of psychiatry - 1 Aug 1995

Higuchi S, Matsushita S, Murayama M, Takagi S, Hayashida M

Abstract excerpt

OBJECTIVE: The authors studied a large number of Japanese alcoholic patients and comparison subjects to establish the genotype frequencies of alcohol dehydrogenase-2 (ADH2) and mitochondrial aldehyde dehydrogenase (ALDH2) and to quantify the relative risk for alcoholism from the results. METHOD:...

Topics

Alcohol Dehydrogenase
Alcoholism
Aldehyde Dehydrogenase
Female
Genotype
Humans
Japan
Male
Middle Aged
Mitochondria, Liver
Odds Ratio
Polymerase Chain Reaction
Polymorphism, Genetic
Risk

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