Article
Alcohol metabolism in Asian-American men with genetic polymorphisms of aldehyde dehydrogenase.
Annals of internal medicine - 1 Sept 1997
Wall T L, Peterson C M, Peterson K P, Johnson M L, Thomasson H R, Cole M, Ehlers C L
Abstract excerpt
BACKGROUND: About half of certain Asians have a deficiency of the low-Km aldehyde dehydrogenase (ALDH2) isoenzyme. This deficiency results from inheritance of a mutant ALDH2*2 allele. OBJECTIVE: To determine whether Asian Americans with ALDH2*2 alleles differ from Asian Americans without this mutation in terms of blood levels of alcohol and acetaldehyde after ingestion of a moderate amount of alcohol. DESIGN:...
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