Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes.

Alcoholism, clinical and experimental research - 1 Feb 1991

Enomoto N, Takase S, Yasuhara M, Takada A

Abstract excerpt

In order to clarify the relationships between acetaldehyde (Ac-CHO) metabolism and low Km (mitochondrial) aldehyde dehydrogenase (ALDH2) genotypes, hepatic ALDH2 activity was determined and serial changes of blood Ac-CHO levels after ethanol administration were analyzed in the individuals homozygous for the normal ALDH2 genes, heterozygous for the normal and mutant ALDH2 genes, and homozygous for the mutant ALDH2...

Topics

Acetaldehyde
Alcoholism
Aldehyde Oxidoreductases
Ethanol
Genetic Carrier Screening
Genotype
Homozygote
Humans
Isoenzymes
Liver
Mutation
Polymerase Chain Reaction

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2024727
DOI: 10.1111/j.1530-0277.1991.tb00532.x

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2024727-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Acetaldehyde metabolism in different aldehyde dehydrogenase-2 genotypes.PMID 2024727Read ↗

Ethanol and acetaldehyde metabolism in chinese with different aldehyde dehydrogenase-2 genotypes.Semantic proximity Read ↗

Alcoholic liver disease in heterozygotes of mutant and normal aldehyde dehydrogenase-2 genes.Semantic proximity Read ↗

Alcohol metabolism in Asian-American men with genetic polymorphisms of aldehyde dehydrogenase.Semantic proximity Read ↗

Role of the aldehyde dehydrogenase-1 isozyme in the metabolism of acetaldehyde.Semantic proximity Read ↗

Effects of aldehyde dehydrogenase-2 genetic polymorphisms on metabolism of structurally different aldehydes in human liver.Semantic proximity Read ↗

Overview of the role of alcohol dehydrogenase and aldehyde dehydrogenase and their variants in the genesis of alcohol-related pathology.Semantic proximity Read ↗

Genetic-epidemiological evidence for the role of acetaldehyde in cancers related to alcohol drinking.Semantic proximity Read ↗

The genetics of alcohol metabolism: role of alcohol dehydrogenase and aldehyde dehydrogenase variants.Semantic proximity Read ↗

Association Between Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism and Alcoholic Liver Disease.Semantic proximity Read ↗

Phenotyping genetic differences in aldehyde dehydrogenase 2 after an alcohol challenge in humansSemantic proximity Read ↗

Characteristics of aldehyde dehydrogenase 2 (Aldh2) knockout mice.Semantic proximity Read ↗

Molecular genetics of human aldehyde dehydrogenase.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.