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Article

Analysis of the genotypes for aldehyde dehydrogenase 2 in Japanese patients with primary gout.

Advances in experimental medicine and biology - 1 Jan 1994

Yamanaka H, Kamatani N, Hakoda M, Terai C, Kawaguchi R, Kashiwazaki S

Abstract excerpt

Alcoholic ingestion is one of the major factors for increasing serum uric acid levels. Genotypes of aldehyde dehydrogenase 2 (ALDH2, E.C.1.2.1.3), which regulates the sensitivity of an individual to ethanol, were determined in Japanese patients with gout and control subjects by allele specific oligonucleotide hybridization using PCR amplified gene. The most common allele ALDH2*1 codes for normal ALDH2 activity,...

Topics

Alcohol Drinking
Aldehyde Dehydrogenase
Alleles
Genetic Carrier Screening
Gout
Homozygote
Humans
Hypoxanthine
Hypoxanthines
Isoenzymes
Japan

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Reference Values

Uric Acid

Source

Identifiers

PMID: 7660963
DOI: 10.1007/978-1-4615-2584-4_13

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7660963-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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