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Article

Novel EGF pathway regulators modulate C. elegans healthspan and lifespan via EGF receptor, PLC‐γ, and IP3R activation

26 May 2010

Abstract excerpt

Improving health of the rapidly growing aging population is a critical medical, social, and economic goal. Identification of genes that modulate healthspan, the period of mid-life vigor that precedes significant functional decline, will be an essential part of the effort to design anti-aging therapies. Because locomotory decline in humans is a major contributor to frailty and loss of independence and because...

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PMID: 20497132
DOI: 10.1111/j.1474-9726.2010.00575.x

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