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Article

Caenorhabditis elegans as a Useful Model for Studying Aging Mutations.

Frontiers in endocrinology - 1 Jan 2020

Zhang Siwen, Li Fei, Zhou Tong, Wang Guixia, Li Zhuo

Abstract excerpt

The Caenorhabditis elegans genome possesses homologs of about two-thirds of all human disease genes. Based on its physiological aging characteristics and superiority, the use of C. elegans as a model system for studies on aging, age-related diseases, mechanisms of longevity, and drug screening has been widely acknowledged in recent decades. Lifespan increasing mutations in C. elegans were found to delay aging by...

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PMID: 33123086
DOI: 10.3389/fendo.2020.554994
PMCID: PMC7570440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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