Article

Broad Effects of Activation of Alcohol Dehydrogenase 1 on Healthspan Extension

2025-11-25

Abstract excerpt

<h4>Summary</h4> Nutritional, genetic, and pharmacological interventions can extend lifespan; however, fewer have been shown to extend healthspan—the period of life free from chronic, debilitating diseases. In line with this, the molecular effectors that drive healthspan are even less understood than those responsible for lifespan extension. We recently reported that activation of Alcohol Dehydrogenase 1 (ADH-1)...

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Literature Corpus work: b5b2886a-35f8-56d9-98dd-1ecf4dad5153
DOI: 10.1101/2025.11.23.687054

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