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Article

Recent progess in phosphoinositide 3-kinases: oncogenic properties and prognostic and therapeutic implications.

Current protein & peptide science - 1 Sept 2010

Wu Guojun

Abstract excerpt

Phosphatidylinositol 3-kinases (PI3Ks) are a group of lipid kinases that coordinate various fundamental cellular responses including mitogenic signaling, cell survival and proliferation, vesicular trafficking, cytoskeletal rearrangement and metabolism. Overexpression caused by genetic alterations such as the amplification or gain of copy numbers was frequently observed for various PI3Ks in different human...

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PMID: 20491626
DOI: 10.2174/138920310791824156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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